RESUMO
BACKGROUND: Advanced age is a well-known risk factor for poor prognosis in COVID-19. However, few studies have specifically focused on very old inpatients with COVID-19. This study aims to describe the clinical characteristics of very old inpatients with COVID-19 and identify risk factors for in-hospital mortality at admission. METHODS: We conducted a nationwide, multicenter, retrospective, observational study in patients ≥ 80 years hospitalized with COVID-19 in 150 Spanish hospitals (SEMI-COVID-19) Registry (March 1-May 29, 2020). The primary outcome was in-hospital mortality. A uni- and multivariate logistic regression was performed to assess predictors of mortality at admission. RESULTS: A total of 2772 consecutive patients (49.4% men, median age 86.3 years) were analyzed. Rates of atherosclerotic cardiovascular disease, diabetes mellitus, dementia, and Barthel Index < 60 were 30.8%, 25.6%, 30.5%, and 21.0%, respectively. The overall case-fatality rate was 46.9% (n: 1301) and increased with age (80-84 years: 41.6%; 85-90 years: 47.3%; 90-94 years: 52.7%; ≥95 years: 54.2%). After analysis, male sex and moderate-to-severe dependence were independently associated with in-hospital mortality; comorbidities were not predictive. At admission, independent risk factors for death were: oxygen saturation < 90%; temperature ≥ 37.8°C; quick sequential organ failure assessment (qSOFA) score ≥ 2; and unilateral-bilateral infiltrates on chest x-rays. Some analytical findings were independent risk factors for death, including estimated glomerular filtration rate < 45 mL/min/1.73 m2; lactate dehydrogenase ≥ 500 U/L; C-reactive protein ≥ 80 mg/L; neutrophils ≥ 7.5 × 103/µL; lymphocytes < 0.8 × 103/µL; and monocytes < 0.5 × 103/µL. CONCLUSIONS: This first large, multicenter cohort of very old inpatients with COVID-19 shows that age, male sex, and poor preadmission functional status-not comorbidities-are independently associated with in-hospital mortality. Severe COVID-19 at admission is related to poor prognosis.
Assuntos
COVID-19/mortalidade , COVID-19/terapia , Mortalidade Hospitalar , Pneumonia Viral/mortalidade , Pneumonia Viral/terapia , Idoso de 80 Anos ou mais , COVID-19/epidemiologia , Feminino , Hospitalização , Humanos , Masculino , Pneumonia Viral/epidemiologia , Prognóstico , Estudos Retrospectivos , Fatores de Risco , SARS-CoV-2 , Espanha/epidemiologiaRESUMO
La promoción de la salud puede ayudar a reducir las desigualdades y velar por la igualdad de oportunidades, proporcionando los medios que permitan a toda la población desarrollar su máximo potencial de salud. Las mujeres que viven en zonas con necesidades de transformación social (ZNTS) son un grupo especialmente vulnerable por la situación de exclusión social y privación material en que viven; los programas de promoción de la salud en este colectivo pueden contribuir a la mejora de su salud. En este trabajo se describe el programa de promoción de la salud Grupos Socioeducativos de Atención Primaria dirigidos a Mujeres (GRUSE-M), y se evalúa su implantación en diversas ZNTS de la ciudad de Sevilla, así como los beneficios y las dificultades de su desarrollo, a través de un análisis documental y de entrevistas a profesionales que lo están implementando
Health promotion can contribute towards reducing inequality and ensuring equal opportunities, providing the means to enable the entire population to develop its maximum health possibilities. Women living in areas with social transformation needs (ASTN) are an especially vulnerable group due to the situation of material deprivation and social exclusion in which they live. Health promotion programmes for this group can bring about an improvement in their health. This paper describes the health promotion programme Socio-educational Groups of Primary Care for Women (SEGPC-W), and evaluates its implementation in ASTN in the city of Seville (Spain), as well as the benefits and difficulties of its development through a documentary analysis and interviews with participating professionals
Assuntos
Humanos , Feminino , Promoção da Saúde/métodos , Saúde da Mulher/tendências , Disparidades nos Níveis de Saúde , Acesso aos Serviços de Saúde/tendências , Serviços de Saúde da Mulher/organização & administração , Marginalização Social , Entrevistas como AssuntoRESUMO
Health promotion can contribute towards reducing inequality and ensuring equal opportunities, providing the means to enable the entire population to develop its maximum health possibilities. Women living in areas with social transformation needs (ASTN) are an especially vulnerable group due to the situation of material deprivation and social exclusion in which they live. Health promotion programmes for this group can bring about an improvement in their health. This paper describes the health promotion programme Socio-educational Groups of Primary Care for Women (SEGPC-W), and evaluates its implementation in ASTN in the city of Seville (Spain), as well as the benefits and difficulties of its development through a documentary analysis and interviews with participating professionals.
